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Adding fatty acid chains or polyethylene glycol to a peptide increases its stability and prevents the digestive system from breaking it down too quickly [2]

While vitamin B12 can be taken orally, many patients will benefit from injections as they allow the vitamin to be absorbed in a higher proportion than other forms of supplementation

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The -hydroxyl of carnitine is acylated so that acyl-coenzyme A (acyl-CoA), which cannot directly cross the inner mitochondrial membrane, can be transported into the mitochondrial matrix and then participate in -oxidation to produce ATP