Who Should NOT Take HRT History of hormone-receptor-positive breast cancer History of blood clots (DVT or pulmonary embolism) Active or history of endometrial cancer Undiagnosed vaginal bleeding Active liver disease Known or suspected pregnancy Uncontrolled hypertension Our Approach to Female HRT Comprehensive Consultation We discuss your symptoms, menstrual history, health history, family history (including breast cancer and cardiovascular disease), current medications, and goals
New England J Med 385(6):503515 Funding Karan Chhabra is supported by KL2 TR001446 from the National Center for Advancing Translational Sciences, National Institutes of Health
However, metformin is not appropriate for people with certain other medical conditions, such as kidney disease, congestive heart failure, metabolic acidosis, and liver issues
This helps prevent overeating and promotes satiety
Preference for Oral Weight Loss Pills Oral Wegovy is the first FDA-approved GLP-1 pill for weight loss and is expected to be available in January 2026
doi:10.1038/nm1196-1254 303
