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Mechanistically, this convergence is mediated by PGC-1, which functions as a central integrator of mitochondrial metabolism and immune regulation downstream of AMPK, SIRT1, and glutamatergic mGluR2 signaling [130,131,132,133]

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Discussion Treatment of T2D patients with GLP-1 analogues results in various beneficial effects, including improvement in -cell function and glucose homeostasis 7

2023 Jul;15(7):377-383

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