Key research themes involving glutathione include: Scavenging of free radicals (e.g., peroxides, nitrogen dioxide, hypochlorous acid) Support of other antioxidant systems (e.g., vitamin C and vitamin E recycling) Detoxification via glutathione S-transferases and related enzymes Regulation of protein folding, disulfide-bond formation, and thiol redox status Modulation of inflammatory mediators, nitric oxide pathways, and cellular metabolism Because endogenous glutathione synthesis capacity appears to decrease with age in many models, glutathione is frequently used as both an experimental variable and a biomarker in studies of aging, disease susceptibility, and redox imbalance
These data suggest that maintenance of circulating triglycerides and sustaining body weight were independent phenotypes in Gclc KO mice
Individualized weight loss pharmacotherapy is recommended, based upon factors such as the specific characteristics of each weight loss medication, the presence of weight-related complications, and the medical history of the patient
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The 2021 European Group on Graves orbitopathy (EUGOGO) clinical practice guidelines for the medical management of Graves orbitopathy
[DOI] [PubMed] [Google Scholar] 31.Chen W, Koenigs LL, Thompson SJ, Peter RM, Rettie AE, et al
