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By selectively inhibiting nicotinamide N-methyltransferase (NNMT), 5-Amino-1MQ helps preserve intracellular NAD+ levels and redirect cellular energy metabolism toward enhanced fat oxidation and mitochondrial efficiency

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However, when multiple comparisons were considered, then a Bonferroni correction was used

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129 Consequently, -cells integrate multiple regulatory inputs to ensure adequate insulin secretion and maintain glucose homeostasis