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However, the unfortunate downside is that this dramatic change is often not sustainable, and many GLP-1 users experience weight rebound after discontinuing their GLP-1 drug

A total of 82 subjects were enrolled (48 in the single-dose part and 34 in the multiple-dose part of the study)

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Slow early results typically indicate timing issues (inconsistent dosing or food timing), insufficient dose elevation, or lifestyle barriers like inadequate sleep or high stress

American Council on Exercise