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Statistical analysis Functional enrichment analysis of differential metabolites in rumen fluid and longissimus dorsi muscle Metabolites with significant differences between the two groups were selected based on t -test p -values and fold change (FC, H-IMF/L-IMF)

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APAP administration increases ROS in the drosophila fat body and depletes systemic glutathione In the mammalian liver, APAP is bio-converted into the toxic metabolite NAPQI by the Cytochrome P450 enzyme CYP2E1 4