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Tirzepatide, with its dual GLP-1/GIP action, may offer additional advantages, particularly in weight loss, fat metabolism, and insulin sensitivity
Small trials suggest potential to reduce cancer-treatment toxicities, but it has not been shown to treat cancer
Recently, Cheng et al
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Intuitively, small increases in ROS would be expected to activate the PI3-K/Akt pathway preferentially, while further increases would be expected to trigger p38MAPK-dependent apoptosis
These changes likely contribute to easier sleep initiation, deeper delta-dominant sleep, and adaptogenic/stress-protective effects without strong sedation
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