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In addition, metformin has no side effects of hypoglycemia [35], which is an independent risk factor for dementia in T2DM patients

Ramsden, C

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Alternative pain management approaches should be considered: Topical NSAIDs gels or creams applied directly to painful areas (e.g., ibuprofen gel for muscle strains) provide localised relief with minimal systemic absorption Physical therapies heat or cold application, gentle exercise, physiotherapy Prescription alternatives your GP may recommend other analgesics depending on pain type and severity For specific pain types , tailored approaches work best