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CCEs contribute to organophosphate resistance, GSTs are linked to resistance to organochlorines like DDT, and MFOs are frequently linked to resistance to pyrethroids like permethrin

Yu MH, Lee JM, Baek JH, Han JK, Choi BI

doi: 10.3347/kjp.2022.60.1.15

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The glucagon component adds three distinct mechanisms: increased hepatic energy expenditure and thermogenesis (increasing resting metabolic rate by an estimated 100-200 kcal/day), enhanced hepatic fatty acid beta-oxidation (directly reducing liver fat), and lipolysis in both hepatic and adipose tissue