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Many patients experience improvement in GI symptoms over time with continued treatment

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Accurate home blood pressure monitoring is strongly recommended, with validated cuff meters (not wrist models)

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General Procedure D for Deprotection of GDP 6a to 6i to GDP 7a to 7i The solution of GDP 6a to 6i was adjusted to a pH of 1.5 by carefully adding an aqueous solution of HCl ( c = 0.25 M) and then stirred overnight at 4 C