For the specific semaglutide methylcobalamin ODT formulation, using methylcobalamin makes pharmacological sense given the buccal absorption route
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Subsequently, the samples were centrifuged for 5 min at 12,000 g , and the supernatants were collected for the detection of PLC activity, using the mouse PLC activity detection kit (Jianglai Biotechnology Company, Shanghai, China) according to the manufacturers instructions
