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Discussion The management of rheumatoid arthritis (RA) has long been dominated by strategies targeting synovial inflammation, often overlooking the pivotal role of chondrocyte dysfunction in joint destruction [35, 36]

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However, plexiform neurofibromas and MPNSTs have similar MRI findings, including areas of low to intermediate signal intensity on T1-weighted sequences and high signal intensity on T2-weighted sequences with heterogeneous enhancement