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When pernicious anaemia is suspected, testing for anti-intrinsic factor antibodies (and sometimes anti-parietal cell antibodies) is recommended

For subcutaneous injections, pinch the skin and poke the needle in at a 90-degree angle, almost like you're throwing a dart, so it barely goes beneath the surface

The injections are generally well-tolerated

NICE guidance on obesity (CG189) and associated quality standards emphasise the importance of structured follow-up for patients who have undergone bariatric procedures, including regular nutritional blood tests and access to dietetic support

Vitamin B12 injections may not be suitable for people who have a history of: allergic reaction or sensitivity to cobalt or vitamin B12 Leber disease kidney disease or impaired kidney function Also, vitamin B12 injections may not be necessary for people without a deficiency

They are intended to support weight-loss efforts as part of a larger wellness plan that includes diet and exercise.