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Many natural and synthetic substrates used by laccases have an ortho -methoxy substituent on the phenol, an electron-donating moiety that facilitates oxidation 29

Backonja M, Beydoun A, Edwards KR, Schwartz SL, Fonseca V, Hes M, et al

In terms of co-occurring symptoms, altered eating experience frequently coexists with gastro-oesophageal reflux, early satiety, and reduced appetite (79), suggesting that in a substantial proportion of patients these phenomena may reflect state-dependent responses rather than isolated sensory abnormalities

J., Coyle, C

Although the risk is small, metaplasia makes cancerous changes more likely

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