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13 See FIGURE 1 for a summary of current recommendations from the ADA for second-line therapy in patients with T2DM

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A 2024 FDA safety review identified reports of suicidal thoughts in some users, though causality remains unclear

Supplementation with GSH rescues cancer cell survival and growth in cystine-deficient conditions, and this rescue depends on the catabolic activity of -glutamyltransferases

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