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To boost glutathione levels, people may consider consuming foods rich in the amino acids required for its synthesis, such as cysteine-containing foods (e.g., garlic, onions, cruciferous vegetables) or take glutathione supplements (though the effectiveness of oral supplementation is debated)
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Failure or malfunction of this process may lead to various illnesses, including cancer and neurodegenerative diseases (Rousseau and Bertolotti, 2018a)
This microbial shift disrupts multiple gutbrain pathways simultaneously: these shifts coincided with gut barrier disruption (elevated serum endotoxin), triggering elevated hippocampal cytokines (IL-6, TNF-), which in turn suppress Tph2 expression and induce Tph2 hypermethylation (suggesting neuroinflammation and serotonergic suppression), ultimately manifesting as anxiety and depression-like behaviors (Buchenauer et al., 2023)
Glutathione is known for its antioxidant properties, detoxification support, immune function enhancement, skin health promotion, and cellular repair