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Clinical trials so far show that GLP-1s are generally safe and effective for long-term use

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[DOI] [PubMed] [Google Scholar] 140.Aslund F., Berndt K.D., Holmgren A

doi: 10.3390/biom11060900, 187 ShulmanA.WangW.LuoH.BaoS.SearchfieldG.ZhangJ

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Discontinuation due to side effects typically ranges 26% across agents, suggesting most adverse events are manageable rather than prohibitive