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In the phase 1 study, a single infusion produced dose-dependent reductions in PCSK9 and LDL cholesterol, with the highest dose group even showing LDL-C reductions of up to 62%, that is itself very impressive

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2.4% placebo (N=1,961) SURMOUNT-1 mean weight loss / 20.9% body-weight reduction at 72 weeks with tirzepatide 15 mg vs

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Comparative GH-fragment research AOD-9604 is frequently used as a comparator alongside other GH-related peptides to characterise the lipolytic-only profile