were included (3 clinical trials sponsored by #FFCD, 3 cohorts) 48% metastatic, 45% doublet chemo Key findings : Factors predicting severe toxicities after 3 months of chemo : female sex, cognitive impairment in men, low albumin level, doublet chemo, impaired kidney function Factors predicting mortality at 36 months : altered IADL, anemia, increased neutrophil count, metastatic stage, and single agent chemo These results will allow treatment individualization in elderly CRC patients Patients predicted to be at risk of severe toxicities could be offered more intensive monitoring This work was supervised by Pr Thomas Aparicio & Pr Florence Canoui-Poitrine, and funded by #INCa To view or add a comment, sign in AccendoWave - A Pain #Data Company Eli Lilly is calling on European countries to make urgent improvements to their #Alzheimers disease diagnostic testing practices just weeks after nabbing a new approval on the continent for its Alzheimer's therapy Kisunla
J Hypertens (2018) 36(12):2398405
The discussion provides context for understanding both the neuroscience behind addictive behaviors and the tools available to address them
Notably, vitamin D receptor (VDR) expression is widespread in renal tubular and vascular smooth muscle cells, and its signaling appears to exert both protective and potentially adverse effects (3, 5)
GHRP-2 demonstrates synergistic GH release when combined with GHRH or its analogs, as they act through distinct intracellular signaling cascades (cAMP for GHRH versus calcium/PKC for GHRP-2)
We should look for someone willing to follow best practices to guard our long-term health
