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CRC, Boca Raton, pp 97124 Kato H, Okamoto M, Yamashita K, Nakamura Y, Fukumori Y, Nakai K, Kaneko H (2003) J Toxicol Sci 28:1924 Kovaevi TB, Borkovi SS, Pavlovi SZ, Despotovi SG, Saii ZS (2008) Arch Biol Sci Belgrade 60:5966 Kster A, Tea I, Sweeten S, Roz JC, Robins RJ, Darmaun D (2008) Anal Bioanal Chem 390:14031412 Li ZH, Zlabek V, Grabic R, Li P, Randak T (2010) Comp Biochem Physiol C 152:392398 Lomaestro BM, Malone M (1995) Ann Pharmacother 29:12631273 Loughlin AM, Skiles GL, Alberts DW, Schaefer WH (2001) J Pharm Biomed Anal 26:131142 Maciel FE, Rosa CE, Santos EA, Monserrat JM, Nery LEM (2004) Can J Zool 82:18711877 Miszczyk M (2007) Prog Plant Protect 47(4):7578 Mitamura K, Sogabe M, Sakanashi H, Watanabe S, Sakai T, Yamaguchi Y, Wakamiya T, Ikegawa S (2007) J Chromatogr B 855:8897 Monostori P, Wittmann G, Karg E, Tri S (2009) J Chromatogr B 877:33313346 Muriana FJ, Ruiz-Gutierri V, Bolufer J (1993) J Biochem 114:404407 Napierska D, Thebault MT, Pempkowiak J, Skorkowski EF (1997) Oceanologia 39:137146 Pastore A, Federici G, Bertini E, Piemonte F (2003) Clin Chim Acta 333:1939 Pea-Llopis S, Ferrando MD, Pea JB (2002) Chemosphere 47:485497 Piccoli G, Fiorani M, Biagiarelli B, Palma F, Potenza L, Amicucci A, Stocchi V (1994) J Chromatogr A 676:239246 Power A, Sheehan D (1996) Comp Biochem Physiol C 114:99103 Schilderman PA, Moonen EJ, Maas LM, Welle I, Kleinjans JC (1999) Ecotoxicol Environ Saf 44:241252 Tanphaichitr V, Horne DW, Broquist HP (1971) J Biol Chem 246:63646366 Trabesinger AH, Boesiger P (2001) Magn Reson Med 45:708710 Trabesinger AH, Weber OM, Duc CO, Boesiger P (1999) Magn Reson Med 42:283289 Yilmaz K, Keser S, Tuzcu M, Gvenc M, etintas B, Irtegn S, Tastan H, Sahin K (2009) J Anim Vet Adv 8:343347 Acknowledgment Financial support was provided by the Polish Ministry of Research and Higher Education under grants 538-L165-0802-12 and DS 8110-4-0085-1

Vitamin B 12 can also be absorbed by passive diffusion, but this process is very inefficient only about 1% to 2% of the oral vitamin B 12 dose is absorbed passively (2)