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They are generally classified into two categories: the first comprises essential trace elements such as iron (Fe), manganese (Mn), zinc (Zn), and copper (Cu), which are indispensable for maintaining normal physiological functions and homeostasis (Zoroddu et al

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GMP Workshop Level: The synthesis/purification area is Class 10,000 (ISO 7), the freeze-drying/packaging area is Class 100,000 (ISO 8), and the local laminar flow reaches Class 100 (ISO 5)

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However, there are some treatments and lifestyle changes that can help to manage the symptoms