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Standard automated perimetry (SAP) revealed an inferior altitudinal visual field (VF) defect with a mean deviation (MD) of -13.8 dB OD (Fig

Patients with T2DM express a greater number of SGLT2 transporters in the proximal tubule than do healthy individuals and hence glucose reabsorption from the glomerular filtrate is increased in patients with diabetes and glycosuria occurs at a higher blood glucose level (typically approximately 220mg/dl (140)

Pharmacologically mediated, marked initial maternal body weight loss and reductions in body weight gain and food consumption coincided with the occurrence of sporadic abnormalities (vertebra, sternebra, ribs) at 0.075 mg/kg twice weekly (9X human exposure)

Diet and exercise remain the foundation