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Borrell and Samuel, 2014)
From a safety perspective, gastrointestinal adverse effects are the most commonly reported for GLP-1 RAs, with nausea, vomiting, and diarrhea remaining the leading causes of treatment discontinuation [7]
Clearly, the multifaceted benefit profile of GLP-1 agonist drugs greatly transcends just aiding in weight loss, but their ability to quickly slim the waistline while reducing mental food noise and decreasing inflammation remains their biggest draw
Evaluating and avoiding potentially offending medications and stimulants like caffeine, improving sleep patterns, and managing stress with yoga, meditation, or tai-chi can be helpful
Nevertheless, supplementation with 2 mg/d folic acid, 25 mg/d vitamin B6, and 400 g/d B12 during 6 months significantly decreased the homocysteine levels, severity, and disability of migraine attacks (60)