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2020;22(9):e19468

doi: 10.1038/s41420-021-00579-w

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As a histone deacetylase (HDAC) inhibitor, butyrate acts directly on B-cell intrinsic pathways without relying on GPR signaling or serving as an energy substrate

Another study conducted by the University of California found that B12 supplements improved energy levels and reduced fatigue in individuals with chronic fatigue syndrome