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American Journal of Health-System Pharmacy

For best results, pair with a healthy diet, proper hydration, and sunscreen use

Used in Trastuzumab deruxtecan (Enhertu), the AM spacer undergoes self-immolation following the cleavage of the amide bond between the peptide linker (GGFG) and the spacer, releasing the free payload (DXd)

In humans, they can cause esophageal cancer and impact the nervous system

Neonatal diabetes can be transient or permanent