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BAs may modulate gut microbiota through antimicrobial properties, with deconjugated BAs produced by bacterial bile salt hydrolases being much less toxic to gut bacteria

Amplitude O (Effect of Efpeglenatide on Cardiovascular Outcomes) revealed that patients with type 2 DM and CVD or kidney disease receiving once weekly efpeglenatide had a 27% lower incidence of the primary composite outcome and 32% lower risk of a composite renal outcome event compared to those receiving placebo [17]

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Scientists who discovered the Glucagon Yusa peptide (GLP-1) were selected as winners of the Lasker Prize, which is called the U.S