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Die Kategorien richten sich nach dem Schweregrad und danach, ob die gemeldete Nebenwirkung in der Fachinformation des verdchtigten Arzneimittels aufgefhrt wird Besonders wichtig fr die Pharmakovigilanz sind Flle der Kategorie C, die schwerwiegend sind und die nicht in der Fachinformation gelistet werden (siehe Tabelle 1)

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Structural influence of isothiocyanates on expression of cytochrome P450, phase II enzymes, and activation of Nrf2 in primary rat hepatocytes