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Another reason compounded medications are prescribed is if there is a shortage of an FDA-approved medication

As these medications become among the most widely prescribed in the world, the ability to tailor treatment based on genetic profile or to target specific clinical outcomes such as cardiovascular risk reduction could transform prescribing practices well beyond their current primary use in obesity and diabetes management Sources New 23andMe Research Institute Study Identifies Genetic Predictors for GLP-1 Weight Loss Efficacy and Side Effects 23andME April 8, 2026 Genetic variations linked to weight loss, side effects from GLP-1 drugs Reuters April 10, 2026

Even though its FDA-approved to treat type 2 diabetes, patients in clinical trials also lost around 20% of their weight after a year of taking Mounjaro along with lifestyle changes

Despite this, 46% of former users say they would retake the medication

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10.1167/iovs.18-26422 Invest