npj Aging 10 (1), 9
Metformin isnt going to outperform Ozempic , but its a useful tool, especially when paired with behavior change
Nutrients 9:1072 Matsuzawa N, Takamura T, Kurita S, Misu H, Ota T, Ando H, Yokoyama M, Honda M, Zen Y, Nakanuma Y, Miyamoto K, Kaneko S (2007) Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet
1.2% with placebo) [22]
However, there were no significant changes in FEV 1 or FEV 1 /FVC ratio [80]
It directly stimulates pro-opiomelanocortin/cocaine-and-amphetamine-regulated transcript (POMC/CART) neurons and indirectly inhibits neuropeptide-Y/agouti-related protein (NPY/AgRP) neurons through GABA neurotransmission, reducing appetite and promoting weight loss [40]