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It also appears unlikely that GLP1 receptormediated effects on cell survival via ERK1/2 signalling can be clearly separated from activation of cAMP/PKA pathways, not least as ERK1/2 phosphorylation is partly PKA dependent

doi: 10.1038/s41423-021-00669-w 168 ZhangC.YangB.BiazikJ

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moreover, many observations indicate that telomeres tend to shorten with age and that accelerated telomere shortening is a sign for many aging-associated pathological conditions

Glial cells (astrocytes and microglia) play important roles in maintaining CNS homeostasis through some processes, including reduction of oxidative stress