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While a balance of commensal and pathogenic bacteria maintains the gut homeostasis, a predominance of pathogenic bacteria in the gut may arise from inadequate intake of the dietary substrate for gut microbiota, physical damage, and antibiotic use

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En modelos animales preclnicos, dado su carcter de molcula pequea oral-activa, los diseos han contemplado dosificacin por va oral o intraperitoneal segn el protocolo aprobado por el comit de tica institucional, con esquemas de administracin diaria y ventanas de tratamiento que abarcan varias semanas para observar efectos sobre composicin corporal

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