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It is important not to self-treat with high-dose B12 supplements before seeing your GP if you suspect deficiency, as this can interfere with diagnostic blood tests and potentially mask underlying conditions such as pernicious anaemia

The apotransferrin-TFR1 complex is then recycled back to the cell surface for further iron uptake

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31 BanerjeeRRCyphertHAWalkerEMChakravarthyHPeirisHGuXet al

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Science 246 , 382385 (1989)