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Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition

Furthermore, SGLT2 inhibitors may attenuate sympathetic nervous system hyperactivity, a common feature in people with type 2 diabetes mellitus and CKD, potentially through decreasing oxidative stress and inflammation [31,32]

Indeed, the explosion of interest in GLP-1 medications, such as Ozempic and Wegovy, has already begun to generate waves far beyond the healthcare sector

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The TRIUMPH program includes seven other Phase 3 trials (TRIUMPH-1 general obesity 80 weeks, TRIUMPH-2 obesity+T2D, TRIUMPH-3 obesity+CV disease, plus T2D, OSA, and CVOT) with readouts expected during 2026

Telomeres naturally shorten with every cell division, a process directly linked to cellular aging and death