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This showed a rotation of the Arg15 side-chain reminiscent of the conformational change reported above in the WD40 Lys15Ala mutant (Fig

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Dietary l-carnitine increased the antioxidant capability and then relieved liver damage The two dietary LC-treated groups exhibited lower serum MDA than the HF group ( P = 0004) (Fig

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The drug also appeared to be safe and tolerable, with most adverse events being gastrointestinal and waning over time, similar to other GLP-1 medications