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Journal of Pharmacy & Pharmaceutical Sciences
10.1124/jpet.102.036004 J
Figure 2 Caloric RestrictionChanges in Gastric Volume, Compliance, and Accommodation Restrictive procedures reduce gastric volumeindeed, the postoperative period of any form of bariatric surgery is characterized by a significant degree of caloric restriction ( Multiple factors influence satiation including stomach capacitance and emptying
Drugs given concomitantly with narrow therapeutic windows should ensure monitoring is undertaken, especially at initiation of GLP-1 agonists when the effect is most pronounced
Clinicians should maintain a high index of suspicion for alternative diagnoses and investigate appropriately when patients report persistent or severe upper gastrointestinal symptoms
Steady state cellular concentrations (M) and reaction velocities (M/hr) as S varies
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