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In addition, Caveolin-1 (Cav-1), a 21-kDa integral plasma membrane protein is a well-known negative regulator of eNOS activity in vascular endothelial cells 17,18,19,20,21,22

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Specifically, ferrous iron (Fe 2 ) reacts with hydrogen peroxide (HO) to generate highly reactive hydroxyl radicals [34], which initiate non-enzymatic lipid autoxidation and accelerate the propagation of lipid peroxides

Examining associations of folic acid supplements administered to mothers during pre-conceptional and prenatal periods with autism spectrum disorders in their offspring: insights from a multi-center study in China