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Nevertheless, pathways implicated in preclinical studies, including angiogenesis, inflammatory modulation, and collagen remodeling, intersect with biologic systems central to incision healing and complication avoidance, although these mechanistic signals have not been shown to translate into improved clinical outcomes

Neurological effects: Some studies propose that DSIP interacts with GABAergic and NMDA receptor systems, both of which are central to relaxation, mood regulation, and sleep induction

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10.3233/JAD-2011-110116 J

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