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Continuously injecting into the same spot can lead to lipohypertrophy, a buildup of fatty tissue that can hinder absorption, or lipoatrophy, a loss of fat that can cause dents in the skin

While the synergy makes sense, it is still theoretical until proven in dedicated trials or, suboptimally, from data in real-world studies

Wang WJ, et al

After a course of intramuscular injections, I switch to oral B12

18 GLP-1R activation in endothelial cells results in the expression of more endothelial nitric oxide synthase, providing greater amounts of nitric oxide and consequent vasodilation