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Treatment initiation may be accompanied by closer clinical follow-up, lifestyle advice and increased patient engagement, which may influence suicide risk independent of GLP-1 RA effects

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Body composition, not the drug alone, determines the outcome

As fat-burning increases, the weight loss continues, but at a slower pace

Figure 1 shows the milestones of this development

Dysesthesia, an abnormal sensation often described as tingling, burning, or numbness in the skin, appeared in 8.8% of participants on the 9 mg dose and 20.9% on the 12 mg dose, compared to just 0.7% on placebo