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Citing these recent works will both address the reviewers concern about currency and strengthen the argument that GSH-responsive strategies are maturing toward precision, clinically relevant theranostics [20]

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273 In malignant gliomas, BCAT c gene expression has been reported to be positively correlated with M2-type macrophages and Treg markers, 274 and GBM cells with high BCAT c expression can excrete BCKAs through monocarboxylate transporter 1 (MCT1)

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