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The mechanism involved stabilization of the gastric mucosal barrier through enhanced mucus production and reduced oxidative stress markers like malondialdehyde (MDA)

[14] [15] Patients with significant anaemia require monitoring of serum potassium, particularly during loading doses

225 In 2018, Wang et al

A standard research dose (e.g., 100mcg) might produce a mild, barely noticeable flush

Kim SJ, Nian C, Karunakaran S, Clee SM, Isales CM, McIntosh CH

Therefore, B12 from food or oral supplements will be poorly absorbed if: There is low stomach acid due to use of a Proton Pump Inhibitor (PPI) There is low intrinsic factor