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Moreover, insulin resistance leading to increased insulin levels may contribute to miniaturization of hair follicles, worsening androgenic alopecia Purpose of Study This case report aims to document the effects of tirzepatide, a glucagon-like peptide-1 (GLP-1) receptor agonist, on improving hair density in a patient with androgenic alopecia and insulin resistance

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In this regard, the activity of the nutrient/stress-sensing mTORC1 is increased during periods of nutrient abundance, and is conversely inhibited when under nutrient stress, such as reduced intracellular ATP or reduced amino acid availability