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These studies (123125)documented the involvement of AQP8 in modulating H 2 O 2 transport through the plasma membrane, influencing redox signaling pathways associated with leukemia cell proliferation (126, 127)

[DOI] [PMC free article] [PubMed] [Google Scholar] 126.Napolitano A., Manini P., DIschia M

However, bTNF- increased lactate dehydrogenase subunit A (LDHA), IL-6, IL-8, IL-1 and COX-2 expression, which was dependent on glycolysis and the PI3K/Akt pathway

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