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However, the therapeutic effectiveness of NAC for APAP overdose is limited by a narrow optimal administration windowwithin 8 h post-exposureand is further challenged by the increasing incidence of treatment failures in overdose cases (Shingina et al

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Six distinct categories of rats were set up: Control (Control), Glutatyone (GSH), Melatonin (Mel), Carboplatin (CARB) Carboplatin+Glutatyone (CARB+GSH), and Carboplatin+Melatonin (CARB+Mel)