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As research progresses, more individuals are curious about its applications and effects
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Characterization of this blend is limited to physicochemical profiling, structural verification, and stability-focused investigation conducted exclusively under controlled, non-clinical laboratory conditions
NETs are reticular skeletons composed of DNA released by neutrophils outside the cell, to which nuclear proteins (eg, histones), cytoplasmic proteins, granular proteins (eg, neutrophil elastase (NE), myeloperoxidase (MPO)), and antimicrobial peptides, etc., are attached (Figure 1)
The continuous production of ONOO could suppress the activity of glutathione reductase by nitration modification, thus collectively reducing detoxification and blocking DNA damage repair
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