3 The best answer for most people is to use both together through the week
It has not been linked to any notable side effects or toxicity, whether applied topically or via subcutaneous injection
& Schirch, V
(TIF) Figure S8
The antioxidant defense network, composed of antioxidants such as polyphenols, ascorbic acid, vitamin A, -lipoic acid, thioredoxin (Trx), glutathione (GSH), melatonin, coenzyme Q, -carotene, and -tocopherol, along with antioxidant enzymes including catalase (CAT), glutathione S-transferase (GST), glutathione peroxidase (GPx), superoxide dismutase (SOD), and glutathione reductase (GR) ( 3 Core pathological mechanisms of ROS-mediated skin diseases Reactive oxygen species play complex and critical roles in the occurrence and development of skin diseases (Figure 2), with pathological mechanisms involving multiple levels, including abnormal cell signaling pathways, regulation of inflammatory responses, and direct oxidative damage
This is why women in Pakistan, aged around 20s and 30s, begin noticing dullness, uneven skin tone, and hyperpigmentation