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For decades, the prevailing medical theory for widespread pain in ME/CFS and fibromyalgia was "central sensitization." This theory posited that the central nervous system (the brain and spinal cord) had become hyper-reactive, amplifying normal sensory input into severe pain

Free radicals are unstable molecules that can cause oxidative stressa process similar to biological "rusting" that damages proteins, fats, and DNA

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However, Eli Lilly canceled the drugs trial before it was completed