If you purchased a GLP-1 medication through a telehealth platform, keep in mind that you may not always know where it was compounded or under what conditions
Phase II Clinical Data Jastreboff 2023 (NEJM) reported 24.2% bodyweight reduction at 48 weeks - the largest effect size published for any metabolic peptide in clinical trials
The DREAMS-3 data showing superiority over semaglutide for the dual endpoint of glycemic control and weight loss makes mazdutide particularly attractive for the diabetes population
The key point for prescribers is this: truly individualized GLP-1 therapy, whether that means microdosing, split dosing, lifestyle-responsive adjustments, or custom formulations with additives, requires a sterile compounding pharmacy capable of preparing precise, patient-specific injectable formulations under the highest standards of quality and safety
The cause is almost always telogen effluvium driven by rapid weight loss, not direct damage from the active ingredient semaglutide
This often happens if you eat too fast, eat late at night, or lie down right after eating