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The inhibition of sphingolipid biosynthesis disrupts numerous cell functions and signaling pathways, including apoptosis and mitosis, thus potentially contributing to carcinogenesis through an altered balance of cell death and replication [113]

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Key Areas of Preclinical Research Skin and Dermal Matrix Research GHK-Cu is widely studied in fibroblast cultures and skin models, where it has been associated with collagen and elastin synthesis, glycosaminoglycan production, and modulation of metalloproteinase activity

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